The Bills and Patriots kickoff at 4:25 from bitterly cold Highmark Stadium. This story will be updated throughout the ...

James Cook scored two touchdowns, Buffalo’s defense forced three second-half turnovers and the AFC East champion Bills ...

The Buffalo Bills are making their final preparations for Sunday afternoon's matchup with the AFC East rival New York Jets.

The New England Patriots (3-11) and the Buffalo Bills (11-3) meet Sunday in a Week 16 game at Highmark Stadium. Kickoff is ...

Rapp and Hamlin have each missed the last two games and were limited this week in practice which has been an ongoing trend. Lewis has started in place of Rapp, but he is now dealing with a shoulder ...

The Buffalo Bills got the win in Week 16, but that three-point victory came with some nerves. The New England Patriots gave ...

The Buffalo Bills won a nail-biter against the New England Patriots, 24-21, in Week 16 action. The Bills, a massive ...

James Cook will lead the Buffalo Bills into their game versus the New England Patriots at Highmark Stadium on Sunday at 4:25 ...

The Buffalo Bills (11-3) are home at Highmark Stadium to take on division rival New England Patriots (3-11) at 4:25 p.m.

The Bills host the Patriots Sunday afternoon at Highmark Stadium. Here is Sal Maiorana's in-depth preview of the game.

The Bills enter the game as a two-touchdown favorite and have the second-highest point spread in the NFL this week.

NFL Week 16 odds, picks, predictions, TV channel, streaming information for Sunday football game between New England Patriots ...