Genome editing-based therapies typically aim to treat disease by correcting underlying genetic mutations in patient's cells.
A new fluorescent sensor is giving scientists an unprecedented view of how cells respond to DNA damage, capturing the repair process as it unfolds in real time. The tool, developed at Utrecht ...
An INRS team discovers a new family of enzymes capable of inducing targeted cuts in single-stranded DNA . A few years ago, the advent of technology known as CRISPR was a major breakthrough in the ...
Professor Dongsheng Liu of Tsinghua University, Professor Ziyang Hao of Capital Medical University, and Researcher Yuanchen Dong of the Institute of Chemistry, Chinese Academy of Sciences, have ...
Figure 1. Design and synthesis of circAMO . (a) Synthesis of a single-molecule ring by rigid regulation of selectivity; (b) Schematic diagram of circAMO design; (c) Synthesis of circAMO; (d) ...
Francesca Storici consults at Tessera Therapeutics. She has received funding from the National Institutes of Health and the National Science Foundation. Your DNA is continually damaged by sources both ...
The first peer-reviewed journal in the field of human gene therapy, providing all-inclusive coverage of the research, methods, and clinical developments that are driving today's explosion of gene ...
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