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At the heart of bottom-up nanotechnology lies a process driven by thermodynamics and kinetics, rather than the deterministic approaches characteristic of top-down methods. This fundamental difference ...

Many of today’s most successful software companies, from Atlassian and Datadog to Zoom, subscribe to the bottom-up SaaS go-to-market model. In this model, the user purchases software directly from a ...

The human brain is a product of evolution. Many psychotherapies and medications focus on adjusting the activity of brain networks that evolved long ago and helped early Homo sapiens survive and ...

Top-down and bottom-up forecasts are increasingly diverging, and we think 2023 will be largely about how these divergences resolve themselves. In commodities, after a major spike in 2022, top-down ...