Researchers have discovered a novel pain control pathway that links the cingulate cortex in the front of the brain, through the pons region of the brainstem, to cerebellum in the back of the brain.

Scientists have discovered a brain circuit that gives pain its emotional sting, explaining why some hurts linger as suffering. The breakthrough challenges our beliefs about how we process pain and may ...

Salk scientists uncover a key neural circuit in mice that gives pain its emotional punch, opening new doors for treating fibromyalgia, migraine, and PTSD LA JOLLA (July 9, 2025)—Pain isn’t just a ...

New research into the mechanism of the placebo effect sheds light on the brain circuitry involved in pain relief. The study, conducted by scientists at the University of North Carolina (UNC), Stanford ...

So when you touch a hot stove, the nerve endings in your fingers react instantly. But the ouch comes a split-second later, when that information finally reaches your brain. Well, now, scientists have ...

A newly identified brain pathway in mice could explain why placebos, or interventions designed to have no therapeutic effect, still relieve pain. Developing drugs that target this pathway may lead to ...

Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This laboratory model could be used to help explain certain pain syndromes, and ...

Share on Pinterest Researchers say circuits in the brain could help provide pain relief without the use of opioids. Westend61/Getty Images Researchers have identified an alternative pain control ...

Pain isn't just a physical sensation—it also carries emotional weight. That distress, anguish, and anxiety can turn a fleeting injury into long-term suffering. Subscribe to our newsletter for the ...

Scientists created a model of the human pain pathway in a dish by connecting four separate brain organoids. The feat should help them understand sensory disorders like those affecting pain perception.