HIV is a virus. Viruses are microscopic germs that are unable to multiply (replicate) by themselves. Instead, they need to find and infect a cell that will act as a host in which new viruses can be ...

HIV has a cunning strategy—it infects specific immune cells, hijacks their genetic program ... The capsid, despite its size, cleverly mimics the structure of these transporters.

to show how structure–function relationships of Env proteins can inform the design of an effective HIV-1 vaccine. With special emphasis on the variable regions of gp120, we highlight the ...

One major reason why it has been difficult to develop an effective HIV vaccine is that the virus mutates very rapidly, ...

Figure 1: Domain organization and structure of ALIX. The papers discussed here greatly enhance our understanding of how HIV-1 and related viruses make contact with the cellular machinery that they ...

Researchers have shown that they can generate a strong immune response against HIV with two doses of a vaccine given one week apart.

The HIV capsid is a cone-shaped structure that provides a container for viral proteins and enzymes. When the virus enters a target cell, the capsid opens up in a pre-programmed sequence to allow HIV ...

Scientists have identified the protein complex that gives the hepatitis C virus the ability to bind and infect cells.

Efavirenz is an important drug for treating HIV infection, but it causes negative neuropsychiatric effects in roughly 50% of ...

Prior vaccine immunogens have not generated bNAbs with the physical structure ... in people without HIV, and that their ...

The federal government is the primary source of research funding with $489 million of $691 million provided by federal ...

Ragon believes he can succeed where major governments have failed: By bringing together top doctors, scientists and engineers ...