The BMJ: Leading Medical Research, News, Education, Opinion
WEBThe pandemic’s origins, the lab leak theory, and the blame game have been in the headlines again. Despite another war of words, we aren’t any closer to a definitive answer as to where the novel coronavirus came from. Mun-Keat Looi asks why. News. ∙ Fauci is defiant as congressional hearing into covid origins fails to produce smoking gun.
Interpreting an isolated raised serum alkaline phosphatase level in …
WEBApr 3, 2013 · This article discusses the most common causes of raised alkaline phosphatase levels in an asymptomatic patient and provides advice on the relevant investigations. #### Learning points If alkaline phosphatase is raised in an asymptomatic patient and serum bilirubin, liver transaminases, creatinine, adjusted calcium, thyroid …
Interpreting iron studies | The BMJ
WEBJun 15, 2017 · It is essential for uptake of oxygen and its delivery to tissues, utilisation of oxygen by muscle cells, and mitochondrial energy production. 3 Normal iron metabolism and regulation is outlined in Figure 1 ⇓. The adult male body contains 3-5 g of iron. Less than 0.1% of total body iron stores circulate in plasma.
Acute vertigo: getting the diagnosis right | The BMJ
WEBAug 12, 2022 · Vertigo— The sensation of self motion when no self motion is occurring or the sensation of distorted self motion during an otherwise normal head movement. Light-headedness— A feeling you are “going to faint”. Imbalance— A state of being out of equilibrium, or with loss of balance. Gait disorder— A problem or difficulty with walking.
Fetal monitoring in labour: summary and update of NICE guidance
WEBDec 16, 2022 · The new guideline on fetal monitoring emphasises that women are the decision makers; clinicians support decision making. A change in the fetal heart rate pattern indicates a change in the fetal condition. Fetal heart rate monitoring is only one element of fetal assessment in labour. Risk assessment should be performed hourly in labour for all ...
Paroxysmal atrial fibrillation | The BMJ
WEBDec 30, 2021 · Atrial fibrillation is the most commonly encountered cardiac arrhythmia in clinical practice (box 1). 7 Paroxysmal atrial fibrillation (PAF) is intermittent episodes of atrial fibrillation that terminate within seven days either spontaneously or with intervention. 8 This excludes atrial fibrillation that is triggered by transient causes such as ...
Five strategies for clinicians to advance diagnostic excellence
WEBFeb 16, 2022 · ### What you need to know Diagnostic accuracy is an important component of clinical excellence. However, diagnostic errors—failures to establish an accurate and timely explanation of a patient’s health problem or to communicate that explanation to the patient—harm patients worldwide.12 In a recent UK study, diagnostic errors occurred in …
Recent advances in the diagnosis and management of cluster …
WEBMar 16, 2022 · Cluster headache, a primary headache disorder, consists of short (15-180 minutes), frequent (up to eight a day), unilateral attacks of facial pain with associated ipsilateral autonomic features and restlessness. The attacks are suspected to be one of the most painful human experiences, and the disorder is associated with a high rate of …
Interpreting raised serum ferritin levels | The BMJ
WEBAug 3, 2015 · Ferritin is an intracellular iron storage protein and a marker of iron stores. Normal serum ferritin levels vary between laboratories but generally concentrations >300 µg/L in men and postmenopausal women and >200 µg/L in premenopausal women are regarded as elevated. 1 Low ferritin values provide absolute evidence of iron deficiency. …
The PRISMA 2020 statement: an updated guideline for reporting ...
WEBMar 29, 2021 · The Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement, published in 2009, was designed to help systematic reviewers transparently report why the review was done, what the authors did, and what they found. Over the past decade, advances in systematic review methodology and terminology …
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