The SARS-CoV-2 nucleocapsid protein: its role in the viral life …
WEBJan 10, 2023 · The SARS-CoV-2 nucleocapsid (N) protein plays an important role in the coronavirus life cycle, and participates in various vital activities after virus invasion. It has attracted a large amount of attention for vaccine and drug development.
Coronavirus nucleocapsid protein - Wikipedia
WEBThe nucleocapsid (N) protein is a protein that packages the positive-sense RNA genome of coronaviruses to form ribonucleoprotein structures enclosed within the viral capsid. [2] [3] The N protein is the most highly expressed of the four major coronavirus structural proteins. [2]
The SARS-CoV-2 Nucleocapsid Protein and Its Role in Viral …
WEBJun 10, 2021 · Like other coronaviruses, the nucleocapsid (N) protein is one of the most crucial structural components of SARS-CoV-2. This protein shares 90% homology with the severe acute respiratory syndrome coronavirus N protein, implying functional significance.
Virus Nucleocapsid - an overview | ScienceDirect Topics
WEBThe nucleocapsid (N) protein of coronavirus is a multifunctional RNA-binding protein and forms a helical filament structure that is required for the assembly of viral genomic RNA into a ribonucleoprotein complex.
Virus Structure and Classification - PMC - National Center for ...
WEBMay 6, 2016 · The virus capsid functions to protect the nucleic acid from the environment, and some viruses surround their capsid with a membrane envelope. Most viruses have icosahedral or helical capsid structure, although a few have complex virion architecture.
The Coronavirus Nucleocapsid Is a Multifunctional Protein
WEBAug 7, 2014 · The coronavirus nucleocapsid (N) is a structural protein that forms complexes with genomic RNA, interacts with the viral membrane protein during virion assembly and plays a critical role in enhancing the efficiency of …
The SARS-CoV-2 nucleocapsid protein is dynamic, disordered
WEBMar 29, 2021 · The SARS-CoV-2 nucleocapsid (N) protein is an abundant RNA-binding protein critical for viral genome packaging, yet the molecular details that underlie this process are poorly understood.
Structures of the SARS‐CoV‐2 nucleocapsid and their …
WEBSep 11, 2020 · Nucleocapsid (N) protein, which is the major structural component of the virion and is involved in viral replication, assembly and immune regulation, plays key roles in the viral life cycle.
Immunological mechanisms of the nucleocapsid protein in COVID …
WEBFeb 14, 2024 · This investigation delves into the role of the SARS-CoV-2 nucleocapsid (N) protein within the HEK293 cells, shedding light on its influence over apoptosis, interferon signaling, and cytokines...
The SARS-CoV-2 Nucleocapsid Protein and Its Role in Viral ... - PubMed
WEBJun 10, 2021 · Like other coronaviruses, the nucleocapsid (N) protein is one of the most crucial structural components of SARS-CoV-2. This protein shares 90% homology with the severe acute respiratory syndrome coronavirus N protein, implying functional significance.