New Look at RSV Infection: Tissue Clearing and 3D Imaging of the …
WEBJan 28, 2021 · Methods: By combining tissue clearing, 3D microscopy and image processing, we developed a novel visualization tool of RSV infection in undissected mouse lungs. Results: Whole tissue analysis allowed the identification of infected cell subtypes, based on both morphological traits and position within the cellular network.
Respiratory syncytial virus entry and how to block it
WEBFeb 5, 2019 · Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract disease in young children and elderly people. Although the virus was isolated in 1955, an effective RSV vaccine has...
Three-Dimensional Cell Culture Models to Study Respiratory Virus ...
WEBDec 25, 2021 · Then, we review the 3D models that have been used to study the most common respiratory viruses including influenza, parainfluenza, respiratory syncytial virus (RSV) and coronaviruses. Herein, we also explain how 3D models have been applied to understand the novel SARS-CoV-2 infectivity and to develop potential therapies.
Structural landscape of the respiratory syncytial virus ... - Nature
WEBSep 15, 2023 · Human Respiratory Syncytial Virus (HRSV) is a prevalent cause of severe respiratory infections in children and the elderly. The helical HRSV nucleocapsid is a template for the viral RNA...
The Morphology and Assembly of Respiratory Syncytial Virus
WEBAug 20, 2018 · RSV is a pleomorphic enveloped RNA virus in the Pneumoviridae family. Recently, the three-dimensional (3D) structure of purified RSV particles has been elucidated, revealing three distinct morphological categories: spherical, asymmetric, and …
New Look at RSV Infection: Tissue Clearing and 3D Imaging of
WEBJan 28, 2021 · Whole lung clearing and 3D deep imaging represents an unprecedented visualization method of infected lungs to allow insight into RSV pathophysiology and improve the 2D histology analyses.
3D tissue-engineered lung models to study immune responses …
WEBSep 7, 2022 · Further, several models used to study immune responses against respiratory viruses, such as the respiratory syncytial virus, are analyzed, showing how the microenvironment aids in understanding immune responses elicited after viral infections.
3D tissue-engineered lung models to study immune responses
WEBSep 7, 2022 · Further, several models used to study immune responses against respiratory viruses, such as the respiratory syncytial virus, are analyzed, showing how the microenvironment aids in understanding immune responses elicited after viral infections.
WEBRespiratory syncytial virus outlook. outlook. Research round-up. spiratory sy. RSV and flu’s intimate connection. , meaning co-infections are common. Clinical studies of such co-infection...
A three-dimensional A549 cell culture model to study respiratory ...
WEBAug 1, 2020 · Respiratory syncytial virus (RSV) is a primary cause of morbidity and mortality worldwide, affecting infants, young children, and immune-compromised patients; however, currently no vaccine is available for prevention of RSV infections.
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